Cortisol vs Cortisone – Meaning, Definiton, Function & Effects on Body

Cortisol and cortisone are two different hormones that are easily mistaken, however, they have a different meaning, different definition, different function and effects on your body. In this article, we will discuss the meaning and the main differences of Cortisol vs Cortisone, the meaning, definition, function & effects on Body of these two human hormones.

Cortisol Meaning

The hormone cortisol is a catabolic steroid hormone secreted by the adrenal glands. It is often referred to as the stress hormone because its levels increase significantly after physical and emotional stress. In fact, this hormone is much more than an indicator of stress levels in the body, it is very important for almost all functions of the human body. Deficiency or high cortisol levels can lead to serious problems in the body. Under normal circumstances, cortisol levels are highest in the morning between 6.00 am and 8.00 am and during the day gradually decreases and reaches the lowest value at midnight.

Cortisol Function and its effects in the human body

The main role of the cortisol hormone is to regulate blood pressure and functions of the cardiovascular system. Moreover, cortisol regulates the use of proteins, carbohydrates, and fats in the body.

After it is secreted it causes decomposition of the protein, which in its turn leads to the release of amino acids in the blood. Immediately after that, the amino acids are used by the liver to synthesize glucose for energy. This raises the levels of blood sugar, thus providing a greater amount of glucose to the brain. At the same time, other tissues reduce their need for glucose as energy fuel.

Cortisol causes the release of fatty acids (energy source of fat cells, which can be used as fuel for muscles). These two energy management processes prepare the body for the situation, in which it is under stress, and also provides the necessary energy reserves for the brain.

Cortisone Definition

Chemical formula C21H28O5 – Cortisone (17-hydroxy-11-de hydro corticosterone) is a crystalline corticosteroid hormone isolated from the adrenal gland.

Cortisone Function and its effects on the human body

Cortisone reduces local inflammation and is used in the treatment of rheumatic, asthma and allergic conditions.

After a consultation with a doctor, the application of cortisone can be used for knee injections or joint injections.

However, its effect is much weaker than that of cortisol, a hormone produced also by the adrenal cortex.

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